Ismael Zambada Garcia
The Guadalajara Cartel ( Spanish : Cártel de Guadalajara ) was a Mexican drug cartel which was formed in the 1980s by Rafael Caro Quintero , Miguel Ángel Félix Gallardo and Ernesto Fonseca Carrillo in order to ship heroin and marijuana to the United States. Among the first of the Mexican drug trafficking groups to work with the Colombian cocaine mafias, the Guadalajara cartel prospered from the cocaine trade.
Juan Nepomuceno Guerra Cárdenas (July 18, 1915 – July 12, 2001) was a Mexican crime lord, bootlegger, businessman and smuggler who founded the Gulf Cartel , a drug trafficking organization. He is often considered the "godfather" of U.S-Mexico border cartels. 
We have all heard of wealthy businessmen like Bill Gates – but there is also an underworld of incredibly rich and powerful men who control much of the international trade in drugs. Their many successes makes one wonder whether there is any point in having a “war” on drugs – it seems to not be helping a great deal. This list looks at ten of the most powerful drug lords in modern history.